Biopharmaceuticals Biochemistry and Biotechnology, 3rd Edition

Biopharmaceuticals Biochemistry and Biotechnology, 3rd Edition | 24.8 MB

Title: Biopharmaceuticals Biochemistry and Biotechnology, 3rd Edition
Author: Gary Walsh
Category: Pharmacology, Pharmacology, Basic Medical Sciences
Language: English | 563 Pages | ISBN: 978-1394211517

Description:
Updated all-in-one guide to understanding the science, development and manufacture of bio-based therapeutics
Biopharmaceuticals: Biochemistry and Biotechnology is a unique resource on biopharmaceuticals that serves as a comprehensive introduction to both the biopharmaceutical industry and its role within the global pharmaceutical industry. This new edition incorporates all major advances from the past 20 years, including the development of biosimilars, bispecific and other engineered antibody formats, engineered cell-based therapies, RNA-based vaccines, and genome editing techniques. Case studies and application examples demonstrate the entire value chain, from development to approval and manufacturing of all types of biopharmaceuticals, covering antibodies (mAbs), cytokines, nucleic acid therapeutics as well as cell-based and other biotherapeutics. Written by an accomplished instructor and textbook writer who has been working with small and large biotech companies for more than 25 years, Biopharmaceuticals: Biochemistry and Biotechnology covers:

• Protein structure (covering protein folding, stability, engineering and structure prediction, post-translational modifications) and recombinant production
  
• Discovery, development and biopharmaceutical regulation
  
• mAb-based therapeutics and vaccines
  
• Cytokines and growth factors, including interferons, interleukins, haematopoietic growth factors, and colony stimulating factors (CSFs)
  
• Recombinant blood products and therapeutic enzymes, covering clotting disorders, anticoagulants, thrombolytic agents, and enzymes of therapeutic value
  
• Hormones, including insulins, GLP-1 related products, human growth hormone and gonadotropins
  
• Product manufacture (upstream and downstream processing) and analysis, covering API characterization, purity and potency determinations, analytical methodologies, protein content, and contaminant testing
  

Delivering comprehensive coverage of the field, Biopharmaceuticals: Biochemistry and Biotechnology is an essential reference for students and professionals in biotechnology, medical biochemistry, medicinal chemistry, and pharmaceutical technology.

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