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Category: eBooks

Hypoglycaemia in Clinical Diabetes, Second Edition
Hypoglycaemia in Clinical Diabetes, Second Edition By
2007 | 349 Pages | ISBN: 0470018445 | PDF | 9 MB
Hypoglycaemia, leading to confusion and impaired consciousness, is one of the most feared complications of diabetes.Hypoglycaemia in Clinical Diabetes, Second Edition explains the situations in which it arises and how to manage patients to minimize its occurrence. Fully revised and updated, the Second Edition of this practical book addresses all aspects of the clinical management of hypoglycaemia. Features new chapters on hypoglycaemia in Type 2 diabetes, the elderly and nocturnal occurrence, as well as prevention and blood glucose monitoring for detection of hypoglycaemia Edited by two diabetologists with strong international reputations who have made significant contributions to our understanding of hypoglycaemia Hypoglycaemia in Clinical Diabetes, Second Edition is an invaluable reference source for professionals caring for people with diabetes. The book is relevant for all clinicians who treat type 1 diabetes or type 2 diabetes. Praise for the First Edition:"I can strongly recommend this excellent book to all clinicians managing care for diabetic persons in everyday practice...." DIABETOLOGIA "...is extremely comprehensive, well written... highly recommended for those practising clinical diabetes." BRITISH JOURNAL OF CARDIOLOGY "A fascinating book; essential reading for those who feel they need a greater understanding of the subject." DIETETICS TODAYContent: Chapter 1 Normal Glucose Metabolism and Responses to Hypoglycaemia (pages 1-24): Ian A. Macdonald and Dr. Paromita KingChapter 2 Symptoms of Hypoglycaemia and Effects on Mental Performance and Emotions (pages 25-48): Ian J. DearyChapter 3 Frequency, Causes and Risk Factors for Hypoglycaemia in Type 1 Diabetes (pages 49-81): Dr. Mark W. J. StrachanChapter 4 Nocturnal Hypoglycaemia (pages 83-99): Simon R. HellerChapter 5 Moderators, Monitoring and Management of Hypoglycaemia (pages 101-120): Dr. Tristan Richardson and Dr. David KerrChapter 6 Counterregulatory Deficiencies in Diabetes (pages 121-140): Dr. David Kerr and Dr. Tristan RichardsonChapter 7 Impaired Awareness of Hypoglycaemia (pages 141-170): Brian M. FrierChapter 8 Risks of Strict Glycaemic Control (pages 171-189): Stephanie A. AmielChapter 9 Hypoglycaemia in Children with Diabetes (pages 191-215): Dr. Krystyna A. MatykaChapter 10 Hypoglycaemia in Pregnancy (pages 217-237): Dr. Ann E. Gold and Dr. Donald W. M. PearsonChapter 11 Hypoglycaemia in Type 2 Diabetes and in Elderly People (pages 239-264): Dr. Nicola N. Zammitt and Brian M. FrierChapter 12 Mortality, Cardiovascular Morbidity and Possible Effects of Hypoglycaemia on Diabetic Complications (pages 265-283): Dr. Miles Fisher and Simon R. HellerChapter 13 Long?Term Effects of Hypoglycaemia on Cognitive Function and the Brain in Diabetes (pages 285-307): Dr. Petros Perros and Ian J. DearyChapter 14 Living with Hypoglycaemia (pages 309-332): Brian M. Frier




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Category: eBooks

Hydrodynamics and Water Quality Modeling Rivers, Lakes, and Estuaries
Hydrodynamics and Water Quality: Modeling Rivers, Lakes, and Estuaries By Zhen?Gang Ji(auth.)
2008 | 692 Pages | ISBN: 0470135433 | PDF | 21 MB
Mathematical modeling for environmental and water resources management This hands-on reference illustrates the principles, basic processes, mathematical descriptions, and practical applications of modeling surface waters. It discusses hydrodynamics, sediment processes, toxic fate and transport, and water quality and eutrophication in rivers, lakes, estuaries, and coastal waters. There has been great progress in mathematical modeling that simulates surface waters numerically. Modeling is becoming a powerful tool, and this reference gets readers up to speed quickly. Practically organized to facilitate quick reference, Hydrodynamics and Water Quality: Modeling Rivers, Lakes, and Estuaries: Focuses on how to solve environmental problems in surface waters Uses a practical, application-oriented approach: chapters begin with an introduction of basic concepts, proceed to discussions of physical, chemical, and/or biological processes and their mathematical representations, and conclude with real-life case studies Has a companion CD that includes a modeling package and electronic files of numerical models, case studies, and model results, plus other materials to help readers use the models and tools Features case studies that show how to use models appropriate to environmental and water resources management Provides detailed information on how to use the three-dimensional Environmental Fluid Dynamics Code (EFDC) model supported by the EPA This is a must-have reference for environmental scientists, engineers, geologists, chemists, and government regulators, as well as other water quality professionals. It is also an excellent text for graduate students in fields that encompass hydrodynamics and water quality.Content: Chapter 1 Introduction (pages 1-12): Chapter 2 Hydrodynamics (pages 13-112): Chapter 3 Sediment Transport (pages 113-200): Chapter 4 Pathogens and Toxics (pages 201-245): Chapter 5 Water Quality and Eutrophication (pages 247-416): Chapter 6 External Sources and TMDL (pages 417-436): Chapter 7 Mathematical Modeling and Statistical Analyses (pages 437-472): Chapter 8 Rivers (pages 473-508): Chapter 9 Lakes and Reservoirs (pages 509-565): Chapter 10 Estuaries and Coastal Waters (pages 567-634):




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Category: eBooks

Hybrid Culture Japanese Media Arts in Dialogue with the West
Yvonne Spielmann, Anja Welle, Stan Jones, "Hybrid Culture: Japanese Media Arts in Dialogue with the West"
English | 2012 | pages: 277 | ISBN: 0262018373 | PDF | 43,0 mb
An exploration of the tensions between East and West and digital and analog in Japanese new-media art.




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Category: eBooks

Human Drug Metabolism An Introduction, Second Edition
Human Drug Metabolism: An Introduction, Second Edition By Michael D. Coleman(auth.)
2010 | 350 Pages | ISBN: 0470742178 | PDF | 4 MB
Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who already have some understanding of the life sciences. Completely revised and updated throughout, the new edition focuses only on essential chemical detail and includes patient case histories to illustrate the clinical consequences of changes in drug metabolism and its impact on patient welfare. After underlining the relationship between efficacy, toxicity and drug concentration, the book then considers how metabolizing systems operate and how they impact upon drug concentration, both under drug pressure and during inhibition. Factors affecting drug metabolism, such as genetic polymorphisms, age and diet are discussed and how metabolism can lead to toxicity is explained. The book concludes with the role of drug metabolism in the commercial development of therapeutic agents as well as the pharmacology of some illicit drugs.Content: Chapter 1 Introduction (pages 1-11): Chapter 2 Drug Biotransformational Systems - Origins and Aims (pages 13-22): Chapter 3 How Oxidative Systems Metabolize Substrates (pages 23-64): Chapter 4 Induction of Cytochrome P450 Systems (pages 65-92): Chapter 5 Cytochrome P450 Inhibition (pages 93-123): Chapter 6 Conjugation and Transport Processes (pages 125-157): Chapter 7 Factors Affecting Drug Metabolism (pages 159-212): Chapter 8 Role of Metabolism in Drug Toxicity (pages 213-267):




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Category: eBooks

How to win at Mathematics A guide to turn yourself from a poor math student into an outstanding one
Sahil Bora, "How to win at Mathematics: A guide to turn yourself from a poor math student into an outstanding one"
English | 2014 | ISBN: 1542447011 | ASIN: B00JC0Y8KW | EPUB | pages: 40 | 0.5 mb
INTRODUCING: The How To Win At Mathematics BookA Guide To Turn Yourself From A Poor Math Student Into An Outstanding OneWhat is The 'How To Win At Mathematics eBook'?Breaking Down How To Learn Math Effectively Using Real Life Examples You Can Use Right Now To Smash Your Next Math AssessmentMath can be difficult and intimidating, especially when you have been going to every class, doing the homework problems and studying your ass off with still nothing to show for it...Learn the exact process which top math students use to ace their assessments, without the stress, frustration, and painful long hours we're all accustomed to. Unlock Your Math Intuition Which Has Been Hiding Away For Years With Creative Tools Including Visualisation, Diagramming, Analogies And SimplificationMathematical insight can be worth a thousand words. But an insight made so simple that it can easily tattooed in your brain is worth a million words...Why? Because that way you don't have to rack your brains resorting to rote memorising before an assessment knowing that what you've learnt is actually going to stick. These tools in learning math will make you learn mathematical concepts quickly without having to spend hours re-reading and drilling problems. Includes My "Assessment Domination Guide" That Will Get You The Grades You DeserveMath is all about problem solving. But not all problems are simple to solve especially when taught by university professors who can't break it down to a 6th grader's level. With very little study, you'll be able to quickly prepare and walk into any assessment calm and confident instead of anxious and confused thanks to my "Assessment Domination Guide". What's Inside How To Win At Mathematics eBook?Maximising Your Attendance in ClassesWhat if I could tell you the secret advantages of why regularly attending class gives you several major advantages even if your tired, don't feel like it or completely hungover from the night before. Do you hate having to spend unnecessary hours rewriting your notes again clearly and remember what was taught in class for an assessment?Most students don't know what to focus on in math classes. But in my 'Note taking' chapter, I will show you the important things to note down and what you can skip. Optimise Your Brain For Learning MathThey say mathematical insight is worth a thousand words. But once you truly understand these insights, they become worth a million words, because I've provided you the learning tools, these insights you learn can easily be tattooed in your brain for years. These tools for obtaining and understanding true mathematical insight will help you quickly learn and understand some of the most complex mathematical concepts...so that you don't have to spend hours pulling all nighters, resorting to rote memorisation to try and learn difficult math concepts before an assessment. If you're like me who's likes learning creatively and visually, then using these learning tools will offer you a solid foundation for learning even the most complex and abstract mathematical concepts. Get Your GradeMath is all about problem solving. But not all problems are simple to solve especially when taught by university professors who can't break it down to a 6th grader's level. With very little study, you'll be able to quickly prepare and walk into any assessment calm and confident instead of anxious and confused thanks to my "Assessment Domination Guide".




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Category: eBooks

How to Read Faster and Recall More Ed 3
Gordon Ray Wainwright, "How to Read Faster and Recall More Ed 3"
English | ISBN: 1845281624 | 2007 | 120 pages | AZW3 | 12 MB
In today's information-laden and time-constrained world we are required to digest an increasing amount of written and printed material. Most people, in their capacity as student, job seeker, employee or leisure reader, want to be able to deal with their daily reading faster and also recall it effectively. This book gives you the means to do just that by: finding the techniques for improvement that work best for you; providing methods for increasing retention and recall; promoting flexibility - the key to reading efficiently; offering techniques for developing skim-reading; and, highlighting problem areas and suggesting ways of addressing them. The book contains exercises to facilitate your development and assesses your results throughout, ensuring that you come away reading faster and recalling more.




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Category: eBooks

How to Harness the Power of Volunteers, Board Members in Fund Development
How to Harness the Power of Volunteers, Board Members in Fund Development By
2013 | 69 Pages | ISBN: 1118692101 | PDF | 34 MB
Originally published by Stevenson, Inc., this practical resource helps nonprofit organizations attract and engage volunteers and board members in fund development. It includes strategies for identifying and enlisting them in fund development efforts, keeping them engaged and motivated, communication, training and more.Important topics covered include:Expand opportunities for involvementAdvice for enlisting volunteer solicitorsBoard member responsibilitiesEnable board members to make asksGet your board to assume responsibility for annual giftsVolunteer educationTeam solicitationMajor gift solicitationBusiness advisory councilsInspire board membersCultivate neighborhood ambassadorsPlanned gifts committeesDevelopment committee chairsFormer board membersHigh-powered volunteersVolunteer recognitionDonor involvementPlease note that some content featured in the original version of this title has been removed in this published version due to permissions issues.Content: Chapter 1 Getting Started: Identify How Volunteers Can Help Fund Development Efforts (pages 4-6): Chapter 2 Volunteer Recruitment Strategies (pages 7-10): Chapter 3 Attracting and Engaging Board Members (pages 11-17): Chapter 4 Planning Procedures - Getting Involvement Early on (pages 18-20): Chapter 5 Training and Education Procedures (pages 21-28): Chapter 6 Involvement through Committees and Advisory Groups (pages 29-33): Chapter 7 Engaging Volunteers and Board Members in Annual Giving Efforts (pages 34-37): Chapter 8 Volunteer Roles in Your Planned Giving Program (pages 38-40): Chapter 9 Engaging Fellow Employees in Fund Development (pages 41-43): Chapter 10 Turn to Retired Employees, Former Board Members for Help (pages 44-45): Chapter 11 Engaging Volunteers and Board Members in Major Gifts Efforts (pages 46-49): Chapter 12 Involving Volunteers and Board Members in Your Capital Campaign (pages 50-53): Chapter 13 Communicating with Board Members and Volunteers (pages 54-58): Chapter 14 Management Issues (pages 59-62): Chapter 15 Showing Appreciation and Recognition to Volunteers and Board Members (pages 63-64): Chapter 16 More Examples of How to Involve Volunteers, Board Members in Fund Development (pages 65-69):




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Category: eBooks

How To Start A Business Small Business To Global Success
How To Start A Business: Small Business To Global Success: How To Create A Successful Merger Or Acquisition Using Crowdfunding by Will Weiser
English | 2022 | ISBN: N/A | ASIN: B0B7MZMM2H | 95 pages | EPUB | 0.18 Mb
If you want to discover how to start a small business and scale it to a global success, this book is for you!




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Category: eBooks

How Tennis Strokes Work The Untaught Laws that Define Proper Tennis Technique
Julius Gavin, "How Tennis Strokes Work: The Untaught Laws that Define Proper Tennis Technique"
English | 2022 | ASIN: B0B436HBPQ | EPUB | pages: 55 | 0.2 mb
This is the world's first perfect book on tennis technique.




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Category: eBooks

Hound Pound Narrative Sexual Offender Habilitation and the Anthropology of Therapeutic Intervention
James B Waldram, "Hound Pound Narrative: Sexual Offender Habilitation and the Anthropology of Therapeutic Intervention"
English | 2012 | pages: 284 | ISBN: 0520272552, 0520272560 | PDF | 1,4 mb
This is a detailed ethnographic study of a therapeutic prison unit in Canada for the treatment of sexual offenders. Utilizing extensive interviews and participant-observation over an eighteen month period of field work, the author takes the reader into the depths of what prison inmates commonly refer to as the "hound pound." James Waldram provides a rich and powerful glimpse into the lives and treatment experiences of one of society's most hated groups. He brings together a variety of theoretical perspectives from psychological and medical anthropology, narrative theory, and cognitive science to capture the nature of sexual offender treatment, from the moment inmates arrive at the treatment facility to the day they are relased. This book explores the implications of an outside world that balks at any notion that sexual offenders can somehow be treated and rendered harmless. The author argues that the aggressive and confrontational nature of the prison's treatment approach is counterproductive to the goal of what he calls "habilitation" - the creation of pro-social and moral individuals rendered safe for our communities.




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Category: eBooks

Horticultural Reviews, Volume 39
Horticultural Reviews, Volume 39 By
2012 | 466 Pages | ISBN: 1118096789 | PDF | 3 MB
Horticultural Reviews presents state-of-the-art reviews on topics in horticultural science and technology covering both basic and applied research. Topics covered include the horticulture of fruits, vegetables, nut crops, and ornamentals. These review articles, written by world authorities, bridge the gap between the specialized researcher and the broader community of horticultural scientists and teachers. Content: Chapter 1 Frankincense, Myrrh, and Balm of Gilead: Ancient Spices of Southern Arabia and Judea (pages 1-76): Shimshon Ben?Yehoshua, Carole Borowitz and Lumir Ondrej HanusChapter 2 Advances in the Biology and Management of Monosporascus Vine Decline and Wilt of Melons and Other Cucurbits (pages 77-120): Roni Cohen, Shimon Pivonia, Kevin M. Crosby and Ray D. MartynChapter 3 Ornamental Grasses in the United States (pages 121-152): Mary Hockenberry MeyerChapter 4 Mediterranean Stone Pine: Botany and Horticulture (pages 153-201): Sven Mutke, Rafael Calama, Santiago C. Gonzalez?Martinez, Gregorio Montero, F. Javier Gordo, David Bono and Luis GilChapter 5 Pointed Gourd: Botany and Horticulture (pages 203-238): Sanjeev Kumar and B. D. SinghChapter 6 Physiology and Functions of Fruit Pigments: An Ecological and Horticultural Perspective (pages 239-271): Willem J. SteynChapter 7 Ginger: Botany and Horticulture (pages 273-388): V. A. Parthasarathy, V. Srinivasan, R. R. Nair, T. John Zachariah, A. Kumar and D. PrasathChapter 8 Annatto: Botany and Horticulture (pages 389-419): Freddy Leal and Claret Michelangeli de Clavijo




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Category: eBooks

Horticultural Reviews, Volume 27
Horticultural Reviews, Volume 27 By
2001 | 387 Pages | ISBN: 0471387908 | PDF | 23 MB
Horticultural Reviews is an ongoing series presenting state-of-the-art review articles on research in the production of commercial horticultural crops: vegetables, fruits, nuts, and ornamental plants of commercial importance. Articles perform the valuable function of collecting, comparing, and contrasting the primary journal literature in order to form an overview of the topic. This detailed analysis bridges the gap between the specialized researcher and the broader community of horticultural scientists.Content: Chapter 1 The Molecular Biology of Flowering (pages 1-39): Steve van NockerChapter 2 Floral Homeotic Gene Regulation (pages 41-77): Robert G. Franks and Zhongchi LiuChapter 3 Lingonberry: Botany and Horticulture (pages 79-123): Inger Hjalmarsson and Rodomiro OrtizChapter 4 Caper Bush: Botany and Horticulture (pages 125-188): Gabriel O. SozziChapter 5 Water Relations and Irrigation Scheduling in Grapevine (pages 189-225): M. H. Behboudian and Zora SinghChapter 6 Physiology and Biochemistry of Superficial Scald of Apples and Pears 227 (pages 227-267): Morris IngleChapter 7 Health Functional Phytochemicals of Fruit (pages 269-315): Wilhelmina KaltChapter 8 Producing Sods over Plastic in Soilless Media (pages 317-351): Henry F. Decker




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Category: eBooks

Horticultural Reviews, Volume 17
Horticultural Reviews, Volume 17 By
1996 | 463 Pages | ISBN: 0471573353 | PDF | 28 MB
Horticultural Reviews present state-of-the-art reviews on topics in horticultural sciences. The emphasis is on applied topics including the production of fruits, vegetables, nut crops, and ornamental plants of commercial importance. It is a serial that appears in the form of one hardbound volume per year.Content: Chapter 1 Mechanical Stress Regulation of Plant Growth and Development (pages 1-42): Cary A. Mitchell and Patricia N. MyersChapter 2 Volatile Emissions from Plants (pages 43-72): Craig S. Charron, Daniel J. Cantliffe and Robert R. HeathChapter 3 A Physiological-Genetic Model of Photoperiod-Temperature Interactions in Photoperiodism, Vernalization, and Male Sterility of Plants (pages 73-123): Weikai Yan and Donald H. WallaceChapter 4 Environmental Control and Photoautotrophic Micropropagation (pages 125-172): Byoung Ryong Jeong, Kazuhiro Fujiwara and Toyoki KozaiChapter 5 Leaf Blackening in Cut Protea Flowers (pages 173-201): Rodney B. Jones, Robyn McConchie, Wouter G. van Doorn and Michael S. ReidChapter 6 Low?Temperature Sweetening in Roots and Tubers (pages 203-231): W. V. Wismer, A. G. Marangoni and R. Y. YadaChapter 7 Jojoba Domestication and Commercialization in Israel (pages 233-266): A. BenzioniChapter 8 Growth and Ripening of Strawberry Fruit (pages 267-297): P. Perkins?VeazieChapter 9 Control of Phytophthora Diseases of Tree Crops Using Trunk?Injected Phosphates (pages 299-330): David I. Guest, Kenneth G. Pegg and Anthony W. WhileyChapter 10 Origin and Dissemination of Peach (pages 331-379): Miklos Faust and Bela TimonChapter 11 Avocado Rootstocks (pages 381-429): A. Ben? Ya'acov and Esther Michelson




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Category: eBooks

Homage to Adrienne Fontainas Passionate Pilgrim for the Arts
Jane Block, Claude Sorgeloos, "Homage to Adrienne Fontainas: Passionate Pilgrim for the Arts"
English | 2013 | pages: 377 | ISBN: 1433120054 | PDF | 156,8 mb
The twenty-two essays in this volume are contributed by Belgian, French, and American scholars to honor the memory and work of Adrienne Fontainas (1929-2010). The interdisciplinary scholarship this community of international scholars has produced is of lasting importance in underlining the significant role of Brussels from 1870 to 1914. A leading European scholar and bibliophile, Adrienne Fontainas served as Vice President of the International Association of Bibliophiles and membre d'honneur of the Royal Society of Bibliophiles and Iconophiles of Belgium. Her groundbreaking books on the Symbolist poet StГ©phane MallarmГ© and his Brussels' editor Edmond Deman (Edmond Deman Г©diteur : Art et Г©dition au tournant du siГЁcle and Edmond Deman : Publications de la librairie) are model studies of the book publishing trade in France and Belgium.




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Category: eBooks

Holland Flowering How the Dutch Flower Industry Conquered the World
Andrew Gebhardt, "Holland Flowering: How the Dutch Flower Industry Conquered the World"
English | 2014 | pages: 265 | ISBN: 9089646175 | PDF | 1,1 mb
Growing tulip bulbs on the moon, and a tulip shaped island in the North Sea. Frederick Ruysch's wunderkammer and contemporary bloemencorsos. A Dutch-Chinese billionaire, aka the Orchid King, recreates a 'Dutch' town in northeast China complete with a replica of Amsterdam's central station and the International Court of Justice. A retired grower recalls a life in flowers, from the Second World War to the European Union. Dutch development policies in Ethiopia today and its former civilizing mission in Java. Auctions, cooperatives, networking, commodity culture, Dutch masculinity, and globalization. These are some of the imaginaries, themes, curious details, and perspectives you will encounter in this book. All of them pivot around Dutch flower culture today and in the Dutch Golden Age, and directly or indirectly link to Aalsmeer's flower auction, the world's largest, located not far from Amsterdam.




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Category: eBooks

Histological Analysis of Endocrine Disruptive Effects in Small Laboratory Fish
Histological Analysis of Endocrine Disruptive Effects in Small Laboratory Fish By Daniel R. Dietrich, Heiko O. Krieger(auth.)
2009 | 381 Pages | ISBN: 0471763586 | PDF | 62 MB
Timely title assembling the combined knowledge of some of the leading authorities in the field of small fish reproduction - an important topic for risk assessment and registration of chemical, agricultural, and pharmaceutical compounds Provides guidance on the microscopic structure of living tissue and evaluation of the reproductive glands of small laboratory fish Includes state-of-the-art science along with sufficient anatomical and physiological background for understanding and interpreting test results Helps standardize the interpretation of results from aquatic bioassays and field observations, which will also clarify inconsistencies in the current scientific literature Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.Content: Chapter 1 Introduction (pages 1-6): Chapter 2 Fish Species of Interest (pages 7-18): Chapter 3 Sexual Determination, Differentiation, and Gonadal Development (pages 19-65): Chapter 4 Female Gonad Anatomy and Morphology (pages 66-87): Chapter 5 Male Gonad Anatomy and Morphology (pages 88-114): Chapter 6 Endocrine?Disrupting Compounds (pages 115-246): Chapter 7 Determination of Effects of Exogenous Hormones and Endocrine?Like Active Compounds (pages 247-253): Chapter 8 Evaluation of Effects in Fish Gonads (pages 254-269): Chapter 9 Experimental Design and Statistics (pages 270-294): Chapter 10 Conclusions (pages 295-299):




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Category: eBooks

Himmler's Nazi Concentration Camp Guards
Ian Baxter, "Himmler's Nazi Concentration Camp Guards"
English | 2013 | pages: 128 | ISBN: 1848847998 | EPUB | 5,2 mb
This book is the most thorough study yet of the whole process of recruitment, indoctrination and performance of those responsible for the guarding of concentration camp inmates. It is not an attractive subject - the conversion of human beings into murderers and individuals routinely carrying out appalling acts of cruelty are bound to be shocking. But it happened under the Third Reich on a massive scale.




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Category: eBooks

High Content Screening Science, Techniques and Applications
High Content Screening: Science, Techniques and Applications By
2008 | 428 Pages | ISBN: 047003999X | PDF | 50 MB
The authoritative reference on HCS in biological and pharmaceutical research High Content Screening (HCS) has been a leading methodology in toxicology studies for years. Recent advances have broadened the range of applications to encompass new areas. High Content Screening: Science, Techniques, and Applications provides comprehensive coverage of HCS in four sections: * The basics of HCS, from the definition to detailed discussions of component technologies * Examples of HCS used in biological applications and early drug discovery, with an emphasis on applications in oncology and neuroscience * The use of HCS across the drug development pipeline * Data management, data analysis, and systems biology, with guidelines for using the large datasets generated by HCS in systems-level studies With chapters contributed by leading authorities from academia and industry, this guide covers: * A wide range of topics, including assay development, cell culture, image processing, robotics, database architecture and management, model systems for analysis, and more * Focused discussions on imaging in 3D, imaging of tissues for pharmacodynamic studies, and screening of both small molecule and RNAi libraries by HCS * The roles of bench researchers and IT personnel in implementing and maintaining HCS platforms * The challenges and advantages of using HCS today, and a look at future directions With eighty-seven detailed figures readers can refer to in full color on the accompanying CD-ROM, this is the premier, hands-on reference on HCS for researchers in academia, biotechnology, and pharmaceutical companies. It's also an excellent resource for lab managers and graduate students in biochemistry, cell biology, toxicology, and related fields.Content: Chapter 1 Approaching High Content Screening and Analysis: Practical Advice for Users (pages 1-24): Scott Keefer and Joseph ZockChapter 2 Automated High Content Screening Microscopy (pages 25-42): Paul A. JohnstonChapter 3 A Primer on Image Informatics of High Content Screening (pages 43-84): Xiaobo Zhou and Stephen T. C. WongChapter 4 Developing Robust High Content Assays (pages 85-109): Arijit Chakravarty, Douglas Bowman, Jeffrey A. Ecsedy, Claudia Rabino, John Donovan, Natalie D'Amore, Ole Petter Veiby, Mark Rolfe and Sudeshna DasChapter 5 HCS in Cellular Oncology and Tumor Biology (pages 111-143): Steven A. Haney, Jing Zhang, Jing Pan and Peter LaPanChapter 6 Exploring the Full Power of Combining High Throughput RNAi with High Content Readouts: From Target Discovery Screens to Drug Modifier Studies (pages 145-168): Christoph Sachse, Cornelia Weiss?Haljiti, Christian Holz, Kathrin Regener, Francoise Halley, Michael Hannus, Corina Frenzel, Sindy Kluge, Mark Hewitson, Benjamin Bader, Amy Burd, Louise Perkins, Alexander Szewczak, Stefan Prechtl, Claudia Merz, Peter Rae, Dominik Mumberg and Christophe J. EcheverriChapter 7 Leveraging HCS in Neuroscience Drug Discovery (pages 169-187): Myles Fennell, Beal McIlvain, Wendy Stewart and John DunlopChapter 8 Live Brain Slice Imaging for Ultra High Content Screening: Automated Fluorescent Microscopy to Study Neurodegenerative Diseases (pages 189-204): O. Joseph Trask, C. Todd DeMarco, Denise Dunn, Thomas G. Gainer, Joshua Eudailey, Linda Kaltenbach and Donald C. LoChapter 9 High Content Analysis of Human Embryonic Stem Cell Growth and Differentiation (pages 205-224): Paul J. Sammak, Vivek Abraham, Richik Ghosh, Jeff Haskins, Esther Jane, Patti Petrosko, Teresa M. Erb, Tia N. Kinney, Christopher Jefferys, Mukund Desai and Rami MangoubiChapter 10 HCS for HTS (pages 225-247): Ann F. Hoffman and Ralph J. GarippaChapter 11 The Roles of High Content Cellular Imaging in Lead Optimization (pages 249-268): Jonathan A. Lee, Karen Cox, Aidas Kriauciunas and Shaoyou ChuChapter 12 Using High Content Analysis for Pharmacodynamic Assays in Tissue (pages 269-291): Arijit Chakravarty, Douglas Bowman, Kristine Burke, Bradley Stringer, Barbara Hibner and Katherine GalvinChapter 13 High Content Analysis of Sublethal Cytotoxicity in Human HepG2 Hepatocytes for Assessing Potential and Mechanism for Chemical? and Drug?Induced Human Toxicity (pages 293-316): Peter J. O'BrienChapter 14 Open File Formats for High Content Analysis (pages 317-328): Jason R. Swedlow, Curtis Rueden, Jean?Marie Burel, Melissa Linkert, Brian Loranger, Chris Allan and Kevin W. EliceiriChapter 15 Analysis of Multiparametric HCS Data (pages 329-354): Andrew A. Hill, Peter LaPan, Yizheng Li and Steven A. HaneyChapter 16 Quantitative and Qualitative Cellular Genomics: High Content Analysis as an End Point for HT?RNAi Phenotype Profiling Using GE's IN Cell Platform (pages 355-369): David O. Azorsa, Christian Beaudry, Kandavel Shanmugam and Spyro MoussesChapter 17 Optimal Characteristics of Protein-Protein Interaction Biosensors for Cellular Systems Biology Profiling (pages 371-387): Kenneth A. Giuliano, Daniel R. Premkumar and D. Lansing Taylor




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Category: eBooks

Here Be Icebergs
Katya Adaui, Rosalind Harvey, "Here Be Icebergs"
English | 2022 | ISBN: 1913867196 | 130 pages | AZW3 | 0.4 MB
The mysteries of kinship (families born into and families made) take disconcerting and familiar shapes in these refreshingly frank short stories. A family is haunted by a beast that splatters fruit against its walls every night, another undergoes a near-collision with a bus on the way home from the beach. Mothers are cold, fathers are absent―we know these moments in the abstract, but Adaui makes each as uncanny as our own lives: close but not yet understood.




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Category: eBooks

Hedge A Greater Safety Net for the Entrepreneurial Age
Hedge: A Greater Safety Net for the Entrepreneurial Age by Nicolas Colin
English | 2018 | ISBN: 1718917082 | 338 Pages | PDF | 5.9 MB
For three decades we've been living through a paradigm shift. Our world is moving from the fading Fordist age to the ever-strengthening digital age. This shift is as unstoppable as the one that once brought us from railroads and steel mills to Fordist factories. And its impact on our lives is just as radical.




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Category: eBooks

Healthcare Biotechnology A Practical Guide
Dimitris Dogramatzis, "Healthcare Biotechnology: A Practical Guide"
English | 2011 | pages: 664 | ISBN: 0367452278 | PDF | 4,8 mb
Foreseeing and planning for all of the possibilities and pitfalls involved in bringing a biotechnology innovation from inception to widespread therapeutic use takes strong managerial skills and a solid grounding in biopharmaceutical research and development procedures. Unfortunately there has been a dearth of resources for this aspect of the field. Until now.




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Category: eBooks

Hans Holbein Revised and Expanded Second Edition
Pascal Griener, Oskar Bätschmann, "Hans Holbein: Revised and Expanded Second Edition"
English | 2014 | pages: 408 | ISBN: 1780231717 | PDF | 10,5 mb
Hans Holbein the Younger was the leading artist of the Northern Renaissance, yet his life and work are not nearly as well-documented as those of his contemporaries Leonardo da Vinci or Michelangelo. That omission has been remedied with this acclaimed study by Oskar Bätschmann and Pascal Griener. Hans Holbein chronicles the life and oeuvre of Holbein (1497/8-1543), as Bätschmann and Griener apply their considerable knowledge to explore the full range of cultural and social influences that affected him and his work. The artist's friendships with leading thinkers such as Erasmus and Thomas More, the development of his painting style, and the cultural influences on his work are all discussed here in this unparalleled and in-depth biography that will be essential to the bookshelf of every art lover. This second edition includes an expanded introduction and additional images.




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Category: eBooks

Handbook of Poultry Science and Technology, Volume 1
Handbook of Poultry Science and Technology, Volume 1 By
2010 | 773 Pages | ISBN: 047018552X | PDF | 9 MB
A comprehensive reference for the poultry industry-Volume 1 describes everything from husbandry up to preservation With an unparalleled level of coverage, the Handbook of Poultry Science and Technology provides an up-to-date and comprehensive reference on poultry processing. Volume 1 describes husbandry, slaughter, preservation, and safety. It presents all the details professionals need to know beginning with live poultry through to the freezing of whole poultry and predetermined cut parts. Throughout, the coverage focuses on one paramount objective: an acceptable quality and a safe product for consumer purchase and use. The text includes safety requirements and regulatory enforcement in the United States, EU, and Asia. Volume 1: Primary Processing is divided into seven parts: Poultry: biology to pre-mortem status-includes such topics as classification and biology, competitive exclusion, transportation to the slaughterhouse, and more Slaughtering and cutting-includes the slaughterhouse building and required facilities, equipment, and operations; carcass evaluation and cutting; kosher and halal slaughter; and more Preservation: refrigeration and freezing-includes the biology and physicochemistry of poultry meat in rigor mortis under ambient temperature, as well as changes that occur during freezing and thawing; engineering principles; equipment and processes; quality; refrigeration and freezing for various facilities; and more Preservation: heating, drying, chemicals, and irradiationComposition, chemistry, and sensory attributes-includes quality characteristics, microbiology, nutritional components, chemical composition, and texture of raw poultry meat Eggs-includes egg attributes, science, and technology Sanitation and Safety-includes PSE, poultry-related foodborne diseases, OSHA requirements, HACCP and its application, and more Content: Chapter 1 Poultry Biology, Classification, and Trade Descriptions (pages 1-18): Y. H. Hui and Isabel Guerrero?LegarretaChapter 2 Competitive Exclusion Treatment in Poultry Management (pages 19-44): Carita Schneitz and Geoffrey MeadChapter 3 Premortem Handling (pages 45-53): Lorenzo Antonio Duraan?MeleendezChapter 4 Transportation to the Slaughterhouse (pages 55-67): Daniel Mota Rojas, Miguel Gonzalez Lozano and Isabel Guerrero?LegarretaChapter 5 Slaughterhouse Building and Facility Requirements (pages 69-78): Daniel Mota Rojas, Miguel Gonzalez Lozano and Isabel Guerrero?LegarretaChapter 6 Slaughtering Equipment and Operations (pages 79-100): Juana Fernandez?Lopez, Esther Sendra?Nadal and Estrella Sayas?BarberaChapter 7 Poultry Carcass Evaluation and Cutting (pages 101-106): Lorenzo Antonio Duran?MelendezChapter 8 Official Control of Slaughterhouses and Processing Plants (pages 107-119): Nina Kaario and Janne LundenChapter 9 Poultry Packaging (pages 121-129): Alfonso Totosaus?SanchezChapter 10 Kosher Laws in Food Processing (pages 131-181): Joe M. Regenstein and Carrie E. RegensteinChapter 11 Food Production from the Halal Perspective (pages 183-215): Yaakob B. Che Man and Awis Qurni SaziliChapter 12 Biochemical Changes during Onset and Resolution of Rigor Mortis under Ambient Temperature (pages 217-241): Estrella Sayas?Barbera, Juana Fernandez?Lopez and Esther Sendra?NadalChapter 13 Physicochemical Changes during Freezing and Thawing of Poultry Meat (pages 243-261): Alma Delia Alarcon?Rojo and Hector Janacua?VidalesChapter 14 Low?Temperature Storage of Poultry (pages 263-281): Maria Elena Carranco?Jauregui, Silvia Carrillo?Dominguez and Maria De La Concepcion CalvoChapter 15 Engineering Principles of Freezing (pages 283-292): Liliana Alamilla?Beltran, Jose Jorge Chanona?Perez, Jose Fernando Gonzalez?Sanchez and Gustavo F. Gutierrez?LopezChapter 16 Quality of Frozen Poultry (pages 293-306): Esther Sendra?Nadal, Estrella Sayas?Barbera and Juana Fernandez?LopezChapter 17 Quality of Refrigerated Poultry (pages 307-324): Vandana Sohlia and Amarinder S. BawaChapter 18 Refrigeration Equipment and Operations (pages 325-347): Mallika Manral and Amarinder S. BawaChapter 19 Freezing Equipment and Operations (pages 349-375): Martha Yarely Leal RamosChapter 20 Refrigeration and Freezing in Central Facilities and Retail Stores (pages 377-395): K. Radakrishna, Vandana Sohlia and Amarinder S. BawaChapter 21 Refrigeration and Freezing in Industrial Food Facilities (Hospitals, Restaurants, Factories) (pages 397-418): Vandana Sohlia and Amarinder S. BawaChapter 22 Heating, Drying, and Chemicals (pages 419-430): Jose Arturo Garcia?MaciasChapter 23 Irradiation (pages 431-449): Maria Pilar Gonzalez?Santiago, Beatriz Caballero?Santos, Magdalena Tudela?Carrasco and Jose Maria Fernandez?GinesChapter 24 Quality Characteristics of Poultry Products (pages 451-465): Sarah PadillaChapter 25 Chemical Composition and Nutritional Content of Raw Poultry Meat (pages 467-489): Jorge Soriano?SantosChapter 26 Poultry Meat Tenderness (pages 491-514): Casey M. Owens and Jean?Francois C. MeullenetChapter 27 Pale, Soft, and Exudative Poultry Meat (pages 515-531): Casey M. Owens and Jason K. AppleChapter 28 Nutritional and Health Attributes of Eggs (pages 533-578): Yuan Ren, Jianping Wu and Robert RenemaChapter 29 Functional Properties of Egg Components in Food Systems (pages 579-630): Yoshinori Mine and Marie YangChapter 30 Chemical Residues: Pesticides and Drugs (??Agonists and Antibiotics) (pages 631-641): Maria de Lourdes Perez?ChabelaChapter 31 Factors Affecting Microbial Growth in Fresh Poultry (pages 643-654): Carol W. TurnerChapter 32 Basic Principles of the HACCP System in the Poultry Industry (pages 655-665): Chitra WendakoonChapter 33 HACCP in Poultry Slaughterhouses (pages 667-682): Marjatta RahkioChapter 34 Online Inspection (pages 683-701): Kevin ChaoChapter 35 Poultry?Related Foodborne Disease (pages 703-716): Lisa McKeeChapter 36 Poultry?Related Foodborne Diseases in Central and South America (pages 717-735): Gabriel J. Sequeira, Luis E. Marti and Marcelo R. RosminiChapter 37 Overview of Poultry Processing and Workers' Safety (pages 737-751): Y. H. Hui and Isabel Guerrero?LegarretaChapter 38 Poultry?Processing Industry and eTool (pages 753-772): Y. H. Hui and Isabel Guerrero?Legarreta




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HPLC richtig optimiert Ein Handbuch fur Praktiker
HPLC richtig optimiert: Ein Handbuch fur Praktiker By
2006 | 797 Pages | ISBN: 3527314709 | PDF | 13 MB
Content: Chapter 1 Grundsatzliches zur Optimierung (pages 1-154): Dr. Stavros Kromidas, Uwe Dieter Neue, Yung?Fong Cheng, Ziling Lu, Alberto Mendez, Kimvan Tran, Diane M. Diehl, Michael McBrien, Hans?Joachim Kuss and Stefan SchomerChapter 2 Die Charakteristika der Optimierung in einzelnen HPLC?Modi (pages 155-528): Dr. Stavros Kromidas, Veronika R. Meyer, Peter Kilz, M. Quaglia, E. Machtejevas, T. Hennessy, K. K. Unger, Egbert Muller and Markus JuzaChapter 3 Kopplungstechniken (pages 529-586): Michael G. Weller, Peter Kilz, Friedrich Mandel, Klaus Albert, Manfred Krucker, Marc David Grynbaum and Karsten PutzbachChapter 4 Computer?unterstutzte Optimierung (pages 587-650): Lloyd R. Snyder, Loren Wrisley, S. Galushko, V. Tanchuk, I. Shishkina, O. Pylypchenko, W. D. Beinert and Michael PfefferChapter 5 „Anwender berichten" (pages 651-726): Heike Schafer, Christiane Lohaus, Helmut E. Meyer, Katrin Marcus, Hans Bilke, Knut Wagner, Mario Arangio, Federico Riccardi Sirtori, Katia Marcucci, Giuseppe Razzano, Maristella Colombo, Roberto Biancardi and Vincenzo Rizzo




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Great Minds Isaac Newton, Nikola Tesla, and Albert Einstein Founders of the Scientific Age
Mark Steinberg, "Great Minds: Isaac Newton, Nikola Tesla, and Albert Einstein Founders of the Scientific Age"
English | 2016 | ISBN: 1536897930 | ASIN: B01JF86SCG | EPUB | pages: 220 | 0.3 mb
Great Minds: Isaac Newton, Nikola Tesla, and Albert Einstein Founders of the Scientific Age The last four hundred years have been some of the most incredible years in human history. From the 17th century to the 21st century, humans went from being almost universally agrarian with sailing vessels, muskets, and astrolabes being the most cutting edge technology on the planet to an era where the world is almost universally industrial or post-industrial with airplanes, cars, spaceships, computers, widespread electricity, enormous power from coal, oil, and nuclear power, and the ability to produce much more food than was ever possible before the Industrial Revolution. This book describes the lives and ideas of three of the minds who made this transition possible: Isaac Newton, Nikola Tesla, and Albert Einstein. What was it about these men that allowed them to change the world with their ideas how the universe and technology worked? In this book you will learn about how these three men were able to turn their respective worlds upside-down with their unconventional thinking, thirst for knowledge, far-reaching vision for the world, and their shear genius. They all had rather different personalities but what unites them is that they all wanted to know how the world really worked were able to train their minds to accomplish that goal. It wasn't easy for any of them and they all lived in relative isolation developing their ideas and inventions while often receiving opposition from the existing scientific, political, and cultural establishment, but in so doing they were able to transform our understanding of universe and society in a way that led to the birth of the modern scientific age. The Modern World is indebted to these men for good or ill.




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Global Migration Governance from Below Actors, Spaces, Discourses
Global Migration Governance from Below: Actors, Spaces, Discourses
English | 2022 | ISBN: 3031069838 | 137 Pages | PDF (True) | 2 MB
After a long time of neglect, migration has entered the arena of international politics with a force. The 2018 Global Compact for safe, orderly and regular migration (GCM) is the latest and most comprehensive framework for global migration governance. Despite these dynamics, migration is still predominantly framed as a state-centric policy issue that needs to be managed in a top-down manner. This book proposes a difference approach: A truly multi-stakeholder, multi-level and rights-based governance with meaningful participation of migrant civil society. Drawing on 15 years of participant observation on all levels of migration governance, the book maps out the relevant actors, "invited" and "invented" spaces for participation as well as alternative discourses and framing strategies by migrant civil society. It thus provides a comprehensive and timely overview on global migration governance from below, starting with the first UN High Level Dialogue in 2006, evolving around the Global Forum on Migration and Development (GFMD) and leading up to the consultations for the International Migration Review Forum in 2022.




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Category: eBooks

Generative Trance The Experience of Creative Flow
Stephen Gilligan, "Generative Trance: The Experience of Creative Flow"
English | ISBN: 178583388X | 2019 | 308 pages | EPUB | 810 KB
Stephen Gilligan's Generative Trance offers a framework for developing a more creative consciousness and lays out the step-by-step processes by which this can be done. William James used to say that 'the unconscious mind is the horse and the conscious mind is the rider: it's the relationship between the two that is most important.' In Generative Trance renowned trainer Stephen Gilligan shows you how to harness this relationship for a much more powerful and effective therapeutic intervention, and reveals how life can be lived as a great journey of consciousness. Emphasizing that reality and identity are constructed by ourselves, Gilligan explains how generative trance is crucial in creating new realities and possibilities for clients. It is a view that differs markedly from the traditional hypnosis ideas of a client losing control, as well as from Ericksonian approaches that feature a benevolent hypnotist who bypasses the conscious mind to work with a client's unconscious mind. Instead, generative trance stresses a 'disciplined flow' process in which a person's conscious and unconscious minds cooperate to weave a higher consciousness capable of transformational change.




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Freud's Argument for the Oedipus Complex
Freud's Argument for the Oedipus Complex: A Philosophy of Science Analysis of the Case of Little Hans
English | 2023 | ISBN: 1032224088 | 297 Pages | PDF (True) | 7.4 MB
In this close reading of Freudian theory, Jerome C. Wakefield reconstructs Freud's argument for the Oedipal theory of the psychoneuroses, placing the case of Little Hans into a philosophy-of-science context and critically rethinking the epistemological foundations of psychoanalysis.




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Foundations of Forensic Mental Health Assessment
Kirk Heilbrun, "Foundations of Forensic Mental Health Assessment "
English | ISBN: 0195323092 | 2008 | 192 pages | PDF | 1158 KB
Forensic mental health assessment (FMHA) has grown into a specialization informed by research and professional guidelines. This series presents up-to-date information on the most important and frequently conducted forms of FMHA. The 19 topical volumes address best approaches to practice for particular types of evaluation in the criminal, civil, and juvenile/family areas. Each volume contains a thorough discussion of the relevant legal and psychological concepts, followed by a step-by-step description of the assessment process from preparing for the evaluation to writing the report and testifying in court.




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Experience-Based Communication
Experience-Based Communication by Jens Ornbo, Claus Sneppen, Peter Franklin WГјrtz
English | PDF | 2008 | 269 Pages | ISBN : 3540787119 | 7.9 MB
Experience-based Communication is a powerful tool. Companies can use it to bring their values to life and to make their messages accessible and credible. By communicating in a way that can be both sensed and felt, companies can increase their influence on internal and external stakeholders - and existing and potential customers.




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